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Can Genetic Testing Help Identify Risk of Heart Disease in Men and Women?

US researchers have launched a clinical trial in which genetic testing is used to identify men and women at risk of developing heart disease based on their DNA makeup. If proven to be effective in clinical trials, this type of genetic test could be internationally accepted to prevent heart disease – the world’s leading cause of death. “This should be the last century of heart disease.” 2,000 men and women between the ages of 40. and 60 with no history of coronary heart disease. DNA samples will be analyzed to determine whether the participants have genetic markers known to cause heart disease.

Once DNA genotyping is complete, the Dignified team will analyze the genetic markers of each participant to determine whether they have a low, medium or high risk of developing heart disease.

Other health and lifestyle factors will also be considered when determining participants’ risk of heart disease. These include hypertension, diabetes, high cholesterol and whether the participant smokes or is physically active, among others.

“I hope that through the results of this study we will be able to capture even more spirits in the future by performing genetic testing for early prevention of coronary heart disease as a regular clinical tool. This approach will represent a paradigm shift in the prevention of this disease, ”Roberts said.

Previously, studies have found strong DNA links to heart attack.

Research has shown that high cholesterol levels from birth can be caused by a common genetic condition called familial hypercholesterolemia (FH). It can lead to a high risk of coronary heart disease from an early age, and some estimates suggest that by age 70, one in two patients with FH will have had a coronary heart disease. .

In a paper published in the European Journal of Cardiology, a study from Monash University in Australia, explained that DNA testing for early FH by the public health system could identify thousands more people with FH early on, who could provide access to barriers that will save lives.

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